Single-cell analysis of the nervous system at small and large scales with instant partitions

Paul W. Frazel, K. Fricano-Kugler, Aaron A. May-Zhang, Michael R. O’Dea, Priya Prakash, NM Desmet, H. Lee, Rhoda Meltzer, KM Fontanez, P. Hettige, Y. Agam, G. Lithwick-Yanai, D. Lipson, BW Luikart, Jeremy D. Dasen, Shane A. Liddelow

bioRxiv, 2023

Transplanted astrocytes show functional flexibility in the recipient brain

Paul W. Frazel, Priya Prakash

Journal of Neuroscience, 2023

Proteomic profiling of interferon-responsive reactive astrocytes in rodent and human

Priya Prakash#, Hediye Erdjument-Bromage, Michael R. O’Dea, Christy N. Munson, David Labib, Valentina Fossati, Thomas A. Neubert, Shane A. Liddelow#

Glia, 2023

Proteomic alterations and novel markers of neurotoxic reactive astrocytes in human induced pluripotent stem cell models

David Labib, Zhen Wang, Priya Prakash, Matthew Zimmer, Matthew D. Smith, Paul Frazel, Lilianne Barbar, Maria L. Sapar, Peter A. Calabresi, Junmin Peng, Shane A. Liddelow, Valentina Fossati

Frontiers in Molecular Neuroscience, 2022

Amyloid β induces lipid droplet-mediated microglial dysfunction in Alzheimer’s disease

Priya Prakash*, Palak Manchanda*, Evi Paouri, Kanchan Bisht, Kaushik Sharma, Prageeth R. Wijewardhane, Caitlin E. Randolph, Matthew G. Clark, Jonathan A Fine, Elizabeth A. Thayer, Alexis Crockett, Nadia Gasmi, Sarah Stanko, Richard Prayson, Chi Zhang, Dimitrios Davalos, Gaurav Chopra

bioRxiv, 2023

Neurotoxic reactive astrocytes induce cell death via saturated lipids

Kevin A. Guttenplan, Maya K. Weigel*, Priya Prakash*, Prageeth R. Wijewardhane, Philip Hasel, Uriel A Rufen-Blanchette, Alexandra E. Münch, Jacob A. Blum, Jonathan A Fine, Mikaela C. Neal, Kimberly Bruce, Aaron Gitler, Gaurav Chopra, Shane A. Liddelow, Ben Barres

Nature, 2021

One scaffold, different organelle sensors: pH‐activable fluorescent probes for targeting live microglial cell organelles

Krupal P. Jethava*, Priya Prakash*, Palak Manchanda, Harshit Arora, Gaurav Chopra

ChemBioChem, 2021

Monitoring phagocytic uptake of amyloid β into glial cell lysosomes in real time

Priya Prakash*, Krupal P. Jethava*, Nils Korte*, Pablo Izquierdo*, Emilia Favuzzi, Indigo V. L. Rose, Kevin A. Guttenplan, Sayan Dutta, Jean-Christophe Rochet, Gordon Fishell, Shane A. Liddelow, David Attwell, Gaurav Chopra

Chemical Science, 2020

Rapid, refined, and robust method for expression, purification, and characterization of recombinant human amyloid beta 1-42

Priya Prakash*, Travis C. Lantz*, Krupal P. Jethava, Gaurav Chopra

Methods and Protocols, 2019